Preview: England v Wales
It is a vital game, even as a warm-up, for both teams.
England head to Australia for a three-Test 'World Cup revenge' tour - while Wales have an even tougher task when they take on the world's top team, New Zealand, also in three internationals.
Wales flank Dan Lydiate is relishing the match - a shot at revenge against Grand Slam winners England before the ultimate test against the All Blacks.
Warren Gatland's men travel to Twickenham for the first time since the 21-25 loss that ended their Six Nations chances.
Wales then travel to New Zealand on Monday to take on the world champions in their own backyard.
But Lydiate is hoping Sunday's meeting with the Red Rose will turn out more like the historic World Cup triumph last year.
"We've got a chance to play against the Grand Slam winning side and the boys are really looking forward to it.
"We are still scratching our heads now about the first half. It was tough watching it back and nobody wants to feel like we did after that game again, we've just to make sure our preparation is right and we fly into the game.
"All credit to England, they flew into us and we were found wanting. We weren't at the races at all. It's always a big challenge going there but one that you relish. We are looking forward to this weekend to hopefully start the tour off on a strong foot."
Wales fly out to New Zealand just a day after the Twickenham clash before the first Test at Eden Park on May 11.
And Lydiate reckons they are ready to hit the ground running.
He said : "We were in last week and had quite intense sessions. The boys are looking in good shape, everyone is lean and there have been a few personal bests. That shows everyone has been diligent with their training and what they have been eating because we know it's a big tour.
"There has been a lot of rugby played this year but you just focus on the next challenge. This game has soon crept up on us and on Monday we will be flying out to New Zealand. We have a massive game ahead of us that will hopefully put us in good stead to head to New Zealand with confidence."
England, of course, also have revenge on their minds - firstly against Wales, who contributed to England's ignominious departure from the World Cup, the first host nation not to make the play-offs.
New England coach Eddie Jones made no secret of the significance of Sunday's Twickenham outing.
"We've prepared well this week and I'm pleased with the progress the squad have made in the time we've had together," Jones said.
"There's been plenty of energy and enthusiasm and you can tell the lads have enjoyed being back in camp.
"This is an important Test match and a great opportunity for us to play some positive, physical rugby.
"We are a young team learning our craft, Wales are an experienced team; it'll be great test for us.
"We can't wait to get back to Twickenham to play in front of a massive crowd. England versus Wales is a special occasion and we look forward to giving our loyal fans something to cheer about."
Wales coach Warren Gatland also turned up the heat by pointing out the importance of winning on Sunday.
"When you look at the June series ahead, this is a really important match for the squad," Gatland said.
"When looking at previous mid-year tours and planning for New Zealand, we felt we needed greater preparation to prepare us for the step up in intensity and the match against England will provide that for us.
"It will be an important hit-out for both teams and as ever it will be an important Test match as it's England versus Wales at Twickenham.
"There is a lot of continuity in our squad and a great amount of experience and that is going to be vital over the next five weeks."
Players to watch:
For England: Mike Brown is worth more than just a cursory glance, George Ford and Ben Youngs are key players in the backline. The loose trio of Jack Clifford, James Haskell and Teimana Harrison has a very experimental look about it and an opportunity to stake a claim for a starting spot on tour.
For Wales: The backline has a settled look, with the key players for the Welsh No.8 Taulupe Faletau and captain Dan Lydiate. Alun Wyn Jones could once again show why he is rated one of the premier locks in the world.
Head to head: At flyhalf you have George Ford (England) against Dan Biggar (Wales), two men who are the key to their respective backlines' ability to turn opportunities into points. However, the most intriguing of the match's many duels will be at lock - Courtney Lawes (England) against Alun Wyn Jones (Wales).
Recent results:
2016: England won 25-21, London
2015: Wales won 28-25, London (World Cup pool match)
2015: England won 21-16, Cardiff
2014: England won 29-18, London
2013: Wales won 30-3, Cardiff
2012: Wales won 19-12, London
2011: Wales won 19-9, Cardiff
2011: England won 23-19, London
2011: England won 26-19, Cardiff
2010: England won 30-17, London
Prediction: Perhaps who wins is not really important in this game, as it is a trial for both. But starting a tour on the back of a win will certainly help. We think England will take the momentum with them, but their winning margin will be less than 10 points.
Teams:
England: 15 Mike Brown, 14 Anthony Watson, 13 Jonathan Joseph, 12 Luther Burrell, 11 Marland Yarde, 10 George Ford, 9 Ben Youngs, 8 Jack Clifford, 7 James Haskell, 6 Teimana Harrison, 5 Courtney Lawes, 4 Joe Launchbury, 3 Dan Cole, 2 Dylan Hartley, 1 Matt Mullan.
Replacements: 16 Tommy Taylor, 17 Ellis Genge, 18 Paul Hill, 19 Dave Attwood, 20 Matt Kvesic, 21 Danny Care 22 Ollie Devoto, 23 Elliot Daly.
Wales: 15 Liam Williams, 14 George North, 13 Scott Williams, 12 Jamie Roberts, 11 Hallam Amos, 10 Dan Biggar, 9 Rhys Webb (Ospreys), 8 Taulupe Faletau, 7 Dan Lydiate (captain), 6 Ross Moriarty, 5 Alun Wyn Jones, 4 Jake Ball, 3 Samson Lee, 2 Scott Baldwin, 1 Rob Evans.
Replacements: 16 Kristian Dacey, 17 Gethin Jenkins, 18 Rhodri Jones, 19 Josh Turnbull, 20 James King, 21 Lloyd Williams, 22 Rhys Priestland, 23 Gareth Anscombe.
Date: Sunday, May 29
Venue: Twickenham Stadium, London
Kick-off: 15.00 (14.00 GMT)
Expected weather: Sunny periods and becoming warm, with light northeast winds. Some sharp, perhaps thundery showers are possible later. High of 21°C and a low of 11°C.
Referee: Marius Mitrea (Italy)
Assistant referees: John Lacey (Ireland), George Clancy (Ireland)
TMO: Simon McDowell (Ireland)
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