Webb recalled for Wales' trip to Twickers
Webb last played for Wales in September 2015, missing the World Cup, and faces a battle to displace in-form incumbent Gareth Davies.
The game at Twickenham pitches England, unbeaten in their opening three games, against a Welsh side a point adrift in second place in the Six Nations table after drawing with Ireland in their opener.
Added spice comes from the fact that England were beaten 28-25 by Warren Gatland's men in last year's World Cup and never recovered as they slumped to an embarrassing pool stage exit on home soil.