France recall Fofana and Spedding
Fofana, who has 39 caps, was forced to sit out the opening game of the tournament - a 23-21 win over Italy - with a rib injury.
South African-born Spedding, capped 14 times, missed the defeat to Wales with a knee injury.
France squad:
Forwards: Jefferson Poirot (Bordeaux-Bègles), Xavier Chiocci (Toulon), Uini Atonio (La Rochelle), Vincent Pelo (La Rochelle), Rabah Slimani (Stade Français), Guilhem Guirado (Toulon, captain), Camille Chat (Racing 92), Yoann Maestri (Toulouse), Alexandre Flanquart (Stade Français), Sébastien Vahaamahina (Clermont), Paul Jedrasiak (Clermont), Yacouba Camara (Toulouse), Damien Chouly (Clermont), Wenceslas Lauret (Racing 92), Loann Goujon (Bordeaux-Bègles), Antoine Burban (Stade Français), Bernard Le Roux (Racing 92).
Backs: Sébastien Bézy (Toulouse), Maxime Machenaud (Racing 92), Jules Plisson (Stade Français), François Trinh-Duc (Montpellier), Jonathan Danty (Stade Français), Maxime Mermoz (Toulon), Gaël Fickou (Toulouse), Rémi Lamerat (Castres), Wesley Fofana (Clermont), Virimi Vakatawa (FFR), Maxime Médard (Toulouse), Hugo Bonneval (Stade Français), Scott Spedding (Clermont), Djibril Camara (Stade Français).
Agence France-Presse