Vermaak returns to torment Cheetahs scrum
The 28-year-old prop is joined in the front row by hooker Ramone Samuels, with Chad Solomon on the replacements bench alongside Michael Kumbirai.
The only other changes to the forwards come among the replacements, with Sikhumbuzo Notshe and Kobus van Dyk providing loose forward cover.
In the backline Jano Vermaak returns from Springbok duty to take his place at scrumhalf, while there are two changes at the back - with Craig Barry making his Currie Cup debut at fullback and Werner Kok on the wing.
Western Province coach John Dobson said that after the bye week his team is determined to make a strong start to the second half of their campaign.
"It is vital that we produce some good rugby this weekend in order to gain some momentum going forward.
"The players are determined to show what they are capable of and are looking forward to the opportunity to play at Newlands," he said.
Western Province: 15 Craig Barry, 14 Werner Kok, 13 EW Viljoen, 12 Huw Jones, 11 Ruhan Nel, 10 Damian Willemse, 9 Jano Vermaak, 8 Nizaam Carr, 7 Cobus Wiese, 6 Jaco Coetzee, 5 John Schickerling, 4 Chris van Zyl (captain), 3 Wilco Louw, 2 Ramone Samuels, 1 Alistair Vermaak.
Replacements: 16 Chad Solomon, 17 Michael Kumbirai, 18 Sikhumbuzo Notshe, 19 Kobus van Dyk, 20 Dewaldt Duvenage, 21 Robert du Preez, 22 Dan Kriel.
Date: Saturday, September 9
Venue: Newlands, Cape Town
Kick-off: 15.00 (13.00 GMT)
Referee: AJ Jacobs
Assistant referees: Marius van der Westhuizen and Divan Uys
TMO: Shaun Veldsman